Symptoms
Patients with mantle cell lymphoma may or may not have symptoms of their mantle cell lymphoma. Patients with mantle cell lymphoma may or may not have symptoms of their mantle cell lymphoma. The main symptom of mantle cell lymphoma is swollen or enlarged lymph nodes. Swollen lymph nodes are usually caused by an infection and the swelling subsides after the infection clears up. Although such lymph node enlargement due to infection can happen and is often associated with tender lymph nodes that decrease in size after the infection clears. If a person has swollen lymph nodes, but hasn't recently had an infection, or has had an infection but the lymph nodes don’t go away, he or she should see a doctor to determine the cause. Most persons with mantle cell lymphoma have no symptoms; however, symptoms of lymphoma in general may include the following:
Swollen (but usually painless) lymph nodes in the neck, underarms, chest, abdomen, or groin. These lymph nodes are usually hard and not mobile

Unexplained weight loss of greater than 10% of body weight over 6 months of time

Loss of appetite

Chronic fever, without an explanation

Intense night sweats, enough to require changing of bedclothes or sheets
Weakness or fatigue

Coughing, chest pain, or shortness of breath
