{"id":22314,"date":"2025-09-28T20:45:57","date_gmt":"2025-09-29T01:45:57","guid":{"rendered":"https:\/\/cmeded.com\/es\/?page_id=22314"},"modified":"2025-10-05T20:57:42","modified_gmt":"2025-10-06T01:57:42","slug":"2025-09-28-what-is-neuroblastoma","status":"publish","type":"page","link":"https:\/\/cmeded.com\/es\/updates\/2025-09-28-what-is-neuroblastoma\/","title":{"rendered":"2025-09-28 \u00bfQu\u00e9 es el neuroblastoma?"},"content":{"rendered":"<div class=\"qa-page\">\n<h1>\u00bfQu\u00e9 es el neuroblastoma?<\/h1>\n<p>El <strong>neuroblastoma<\/strong> es el tumor s\u00f3lido extracraneal m\u00e1s com\u00fan en los ni\u00f1os y la malignidad m\u00e1s frecuente en los lactantes. Comienza en c\u00e9lulas nerviosas inmaduras y, con mayor frecuencia, se origina en el tejido nervioso de las gl\u00e1ndulas suprarrenales. Sin embargo, tambi\u00e9n puede desarrollarse en el tejido nervioso del cuello, la m\u00e9dula espinal, el t\u00f3rax o el abdomen.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/cmeded.com\/wp-content\/uploads\/2013\/08\/Neuroblastoma-Overview-450-300x221.jpg\" alt=\"Neuroblastoma\" width=\"300\" height=\"221\" class=\"alignnone size-medium wp-image-9845\" \/><\/p>\n<p>El neuroblastoma representa aproximadamente el 7% de todos los c\u00e1nceres infantiles y el 15% de la mortalidad por c\u00e1ncer en la infancia. Suele presentarse en ni\u00f1os menores de cinco a\u00f1os, y casi la mitad de los casos se diagnostican en menores de dos a\u00f1os.<\/p>\n<p>Los nuevos avances publicados por <a href=\"https:\/\/www.nature.com\/nature-portfolio\" target=\"_blank\" rel=\"noopener\">Nature Portfolio<\/a> describen varios casos de supervivientes a largo plazo en el seguimiento de un ensayo cl\u00ednico de fase 1 sobre una <strong>terapia con c\u00e9lulas CAR T<\/strong> modificadas gen\u00e9ticamente, desarrollada en el <strong>Center for Cell and Gene Therapy<\/strong> del <a href=\"https:\/\/www.bcm.edu\/\" target=\"_blank\" rel=\"noopener\">Baylor College of Medicine<\/a>, el <a href=\"https:\/\/www.texaschildrenspeople.org\/\" target=\"_blank\" rel=\"noopener\">Texas Children\u2019s Hospital<\/a> y el <a href=\"https:\/\/www.houstonmethodist.org\/\" target=\"_blank\" rel=\"noopener\">Houston Methodist Hospital<\/a>.<\/p>\n<p>El ensayo (<strong>NCT00085930<\/strong>) fue el primer estudio iniciado en el Center for Cell and Gene Therapy. Diecinueve ni\u00f1os con neuroblastoma recurrente o resistente al tratamiento fueron tratados con c\u00e9lulas CAR T dise\u00f1adas para atacar <strong>GD2<\/strong>, un ant\u00edgeno altamente expresado en la superficie de las c\u00e9lulas de neuroblastoma.<\/p>\n<p>De los 11 pacientes con enfermedad activa en el momento del tratamiento, dos lograron respuestas completas sostenidas \u2014una de ellas durante m\u00e1s de 18 a\u00f1os. De los ocho pacientes sin evidencia de enfermedad activa al momento del tratamiento, cinco permanecieron libres de enfermedad en su \u00faltima revisi\u00f3n, entre 10 y 15 a\u00f1os despu\u00e9s de la infusi\u00f3n.<\/p>\n<p><a href=\"https:\/\/cmeded.com\/es\/childhood\/understanding-neuroblastoma\/overview\/\">Haz clic aqu\u00ed para aprender m\u00e1s sobre el neuroblastoma<\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u00bfQu\u00e9 es el neuroblastoma? El neuroblastoma es el tumor s\u00f3lido extracraneal m\u00e1s com\u00fan en los ni\u00f1os y la malignidad m\u00e1s frecuente en los lactantes. Comienza en c\u00e9lulas nerviosas inmaduras y, con mayor frecuencia, se origina en el tejido nervioso de las gl\u00e1ndulas suprarrenales. Sin embargo, tambi\u00e9n puede desarrollarse en el tejido nervioso del cuello, la [&hellip;]<\/p>\n","protected":false},"author":61,"featured_media":0,"parent":22191,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"tags":[],"class_list":["post-22314","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>CMedEd | Novedades | 2025-09-28 \u00bfQu\u00e9 es el neuroblastoma?<\/title>\n<meta name=\"description\" content=\"\u00bfQu\u00e9 es el neuroblastoma? 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