Signs and Symptoms

Neuroblastoma can cause different symptoms, depending on the location of the primary tumor and whether or not the disease has spread to other parts of the body.

Most common symptoms:
Lump or mass in the abdomen, neck, chest, or back
A lump or mass in the abdomen, neck, chest, or back
Abdominal pain and swelling
Abdominal pain and swelling
Bulging of the eyes
Bulging of the eyes
Dark circles under the eyes
Dark circles under the eyes
Bone pain
Bone pain
Anemia or fatigue
Anemia or fatigue
Easy bruising or bleeding, petechiae
Easy bruising or bleeding, petechiae
Difficulty breathing (in infants)
Difficulty breathing (in infants)
Bluish lumps under skin (in infants)
Bluish lumps under skin (in infants)
Weakness or paralysis (inability to move a body part)
Weakness or paralysis (inability to move a body part)
Unexplained weight loss or loss of appetite
Unexplained weight loss or loss of appetite
Less common symptoms:
Fever
Fever
Difficulty breathing
Difficulty breathing
High blood pressure
High blood pressure
Diarrhea
Diarrhea
Opsoclonus-Myoclonus-Ataxia
Opsoclonus-Myoclonus-Ataxia (Uncontrolled eye movement and jerky muscle movement)