The diagnosis of TNBC often occurs during a clinical or physical examination. This is because tumors with a triple-negative status tend to have an accelerated growth rate when related to the screening intervals. However, TNBC is still seen on mammograms and ultrasounds when present, just as in other types. Additionally, during a biopsy or surgery for breast cancer, sample cells will be tested for estrogen, progesterone, or HER2 receptors. If none of these receptors is present, your doctor will diagnose your cancer as triple-negative.