Certain factors are associated with the occurrence of TNBC.
Women under 40 are more likely to be diagnosed with TNBC than women over 40. Similarly, women who have not yet experienced menopause are at greater risk for TNBC.
Despite a lower incidence of breast cancer in general, African American and Hispanic women are more likely to develop TNBC than women of other racial and ethnic backgrounds.
An alteration in the BRCA1 gene is associated with a heightened risk of developing breast cancer at a younger age, including TNBC.