Risk Factors
A risk factor is a behavior, characteristic, or condition that raises the possibility of developing a disease. Multiple genetic syndromes can predispose to the development of pancreatic neuroendocrine tumors. One hereditary risk factor for islet cell tumors is a condition known as multiple endocrine neoplasia type 1 (MEN1).
Click Image to Enlarge.
Multiple Endocrine Neoplasia Type 1 (MEN1)
MEN1 is an inherited genetic condition that causes tumors to develop in the pituitary gland, parathyroid gland, and pancreas. This disease may increase the risk of developing islet cell tumors in the pancreas.
Other genetic mutations may include von Hipple Lindau syndrome (VHL) and neurofibromatosis type 1 (NF1)
